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SCI(S) Article

Genetics of rheumatoid arthritis contributes to biology and drug discovery
Author
Bang, So-Young (Hosp Rheumat Dis); Lee, Hye-Soon (Hosp Rheumat Dis); Bae, Sang-Cheol (Hosp Rheumat Dis);
Corresponding Author Info
Plenge, RM (reprint author), Harvard Univ, Brigham & Womens Hosp, Sch Med, Div Rheumatol Immunol & Allergy, Boston, MA 02115 USA.
E-mail
Document Type
Article
Source
NATURE Volume:506 Issue:7488 Pages:376-+ Published:2014
Times Cited
137
External Information
http://dx.doi.org/10.1038/nature12873
Abstract
A major challenge in human genetics is to devise a systematic strategy to integrate disease-associated variants with diverse genomic and biological data sets to provide insight into disease pathogenesis and guide drug discovery for complex traits such as rheumatoid arthritis (RA)(1). Here we performed a genome-wide association study meta-analysis in a total of
Web of Science Categories
Multidisciplinary Sciences
Funding
National Institutes of Health (NIH) [R01-AR057108, R01-AR056768, U01-GM092691, R01-AR059648]; Burroughs Wellcome Fund; Japan Society of the Promotion of Science; Australian National Health and Medical Research Council [1036541]; Netherlands Organization f
Language
English
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