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SCI Article

C-H Activation: A Complementary Tool in the Total Synthesis of Complex Natural Products
Author Youn, So Won (Dept Chem); Youn, So Won (Res Inst Nat Sci);
Corresponding Author Info Chen, DYK (reprint author), Seoul Natl Univ, Dept Chem, Seoul 151742, South Korea.
E-mail 씠硫붿씪 븘씠肄
Document Type Review
Source CHEMISTRY-A EUROPEAN JOURNAL Volume:18 Issue:31 Pages:9452-9474 Published:2012
Times Cited 166
External Information PDF 븘씠肄http://dx.doi.org/10.1002/chem.201201329
Abstract The recent advent of transition-metal mediated C?H activation is revolutionizing the synthetic field and gradually infusing a C?H activation mind-set in both students and practitioners of organic synthesis. As a powerful testament of this emerging synthetic tool, applications of C?H activation in the context of total synthesis of complex natural products are beginning to blossom. Herein, recently completed total syntheses showcasing creative and ingenious incorporation of C?H activation as a strategic manoeuver are compared with their non-C?H activation counterparts, illuminating a new paradigm in strategic synthetic design.
Web of Science Categories Chemistry, Multidisciplinary
Funding National Research Foundation of Korea (NRF) [2010-0017149, 2010-0007737]; Ministry of Education, Science and Technology (MEST)
Language English
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